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The Omega-3 Index and Why It Matters

Your Omega-3 Index (O3I) measures how much of the essential fatty acids EPA + DHA are built into your red-blood-cell membranes.

It’s one of the clearest biomarkers for long-term cardiovascular and cognitive health.

When your Omega-3 Index is low, the body struggles to protect itself from inflammation, fatigue, and cardiovascular strain.

When it’s high – around 8% – you’re in the optimal range linked to stronger heart protection, sharper focus, and better overall wellbeing 

  • < 4% – Deficient

    Higher risk for heart and brain issues; common in Western diets.

  • 4-6% – Marginal

    Some intake, but not enough to support performance or resilience.

  • 6-8% – Functional

    Noticeable improvements in focus, stress recovery, and daily health.

  • ≈ 8% – Optimal

    The target zone for cardiovascular protection and cognitive balance.

The problem persists

Despite oceans of supplements, most people in the US and Europe still fall short of this ideal range. Meanwhile, populations in Norway, Iceland, and Japan consistently reach that protective 8%...

Jan Philipp Schuchardt, Philine Beinhorn, Xue Feng Hu, Hing Man Chan, Kaitlin Roke, Aldo Bernasconi, Andreas Hahn, Aleix Sala-Vila, Ken D. Stark, William S. Harris, Omega-3 world map: 2024 update, Progress in Lipid Research,Volume 95,2024,101286, ISSN 0163-7827, https://doi.org/10.1016/j.plipres.2024.101286

Measurably better omega-3 index improvement

Our science isn’t borrowed – it’s built on evidence

In a controlled 3-month clinical study, 60 professional athletes took NFO Omega-3 Forte daily (310 mg EPA + 205 mg DHA). The results demonstrated measurable improvements in cardiovascular and recovery markers.

Omega-3 Index restored – 18% of athletes started below the healthy 8% level; after 3 months, none remained deficient.

Lipid profile transformation

  • Total cholesterol ↓ 9.8%
  • LDL ("bad") cholesterol ↓ 17.2%
  • VLDL ↓ 47.6%
  • Triglycerides ↓ 13.3%
  • Atherogenic index ↓ 36.3%
  • HDL ("good") cholesterol ↑ 22.4%

Daily NFO Omega-3 intake optimizes the Omega-3 Index, enhances endurance, and supports heart and brain health – naturally.

Kruglova I.V., Davidyan O.V. (2017). Effectiveness of Omega-3 Polyunsaturated Fatty Acids in a Complex of Recovery Measures for Athletes. Voprosy Dietologii, 7(3): 20–27. DOI: 10.20953/2224-5448-2017-3-20-27.

Improved metabolic balance and cognitive performance

Clinical studies confirmed that NFO® Omega-3 significantly improves metabolic balance and cognitive performance.

1. Restores the Omega-3 Index

In a 6-month prospective study involving 90 children (ages 3–17) with lipid metabolism disorders, daily supplementation of NFO® Omega-3 (1000–2000 mg EPA + DHA) raised the share of participants with an optimal Omega-3 Index > 8% from 13.3% to 38.8%.

No side effects were reported — only measurable biochemical improvement and faster recovery.

The effect of omega-3 polyunsaturated fatty acid deficiency on the lipid profile and metabolic status of children of various ages withheterogeneous lipid metabolism disorders / I.N. Zakharova [et al.] // Pediatrician’s practice. 2024;(2)

2. Boosts Cognitive Focus

A parallel 6-month clinical study involving 87 children and adolescents (ages 6–17) showed remarkable results.

After daily intake of NFO® Omega-3 (1000 mg):

  • The share of participants achieving an optimal Omega-3 Index > 8% increased from 16.6% to 78.3% — a nearly five-fold improvement.
  • Concentration and attention stability (Bourdon Correction Test) improved significantly (p < 0.05).
  • Children made fewer mistakes and maintained focus longer, showing enhanced neural efficiency and oxygen utilization.

Zakharova IN, Korchagina IuV, Pshenichnikova II. Positive effect of ω-3 polyunsaturated fatty acid supplementation on cognitive functions of childrenand adolescents with lipid metabolism disorders. Pediatrics. Consilium Medicum. 2024;2:***-***. DOI: 10.26442/26586630.2024.2.202930

Most Omega-3 products focus on ingredients

We make sure they work for you.

Clinically Proven Impact

Backed by human studies showing real improvements in cholesterol, triglycerides, and Omega-3 Index | Learn more.

Designed for Human Biology

Formulated to raise your Omega-3 Index and optimize heart, brain, and cell performance in just 3 months | Learn more.

Verified Purity

No heavy metals, no contaminants, and ultra-low oxidation.

Tailored Use Cases

Purpose-built for real needs, from daily support to critical deficiency.

Transparent Science

Every batch published with lab data and oxidation values – full proof, no hype | re: Certificate of Analysis in Products.

Noticeable Results, Naturally

Measurable gains in energy, focus, and recovery | Learn more.

Find the case that works for you

Daily essentials

Formulated with 55 % EPA/DHA, enhanced with krill oil and astaxanthin – designed to help most users maintain an optimal Omega-3 Index.

Omega-3 Forte collection

Sensitive Digestion

A gentle, natural-triglyceride formula that’s easier on the stomach. Available in liquids, softgels, or chewables for smooth absorption and comfort.

TG collection

Difficulty Swallowing

Light, compact mini-softgels made with natural triglycerides or salmon oil. Easy to take, and built to keep your Omega-3 Index in the healthy range.

Mini collection

Critical Deficiency

A high-strength option with 75% re-esterified triglycerides. Specifically engineered to restore low Omega-3 Index levels quickly and effectively.

Critical collection

Significantly better Omega-3

strong DHA omega-3
NFO Vitamins
Omega-3 Strong DHA
¥548.00
¥548.00
best fish oil
NFO Vitamins
Omega-3 Ultima
¥1,162.00
¥1,162.00
omega-3-6-9 salmon oil
NFO Vitamins
Omega 3-6-9 Salmon Oil
¥548.00
¥548.00

Learn more

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